Monzurul Alam, PhD

Interdisciplinary Division of Biomedical Engineering,
The Hong Kong Polytechnic University,
Hong Kong.

Md. Monzurul Alam, PhD

Contact Information

Phone: +852 6213 5054
Fax: +852 2334 2429
Email: md.malam@connect.polyu.hk
Web: www.biorehab.org

Key Research

Neurorehabilitation: Spinal Cord Injury (SCI) and Stroke Rehabilitation, Neuromodulation, Functional Electrical Stimulation (FES), Gait Rehabilitation, Neural circuits and their plasticity.

Neuroprosthetics: Sensorimotor Neuroprostheses, Brain-machine Interfacing (BMI), Peripheral Nerve Interfacing, Bionic Prostheses (Artificial Limb, Myoelectric Hand, Hybrid Bionics).

I am an electrophysiologist and neuroengineer. I was primarily trained in electronic engineering, but spent the last 8-10 years in neuroscience and biomedical engineering with aim to develop advanced neuroprostheses and rehabilitation stratigies for the paralyzed patients. I pursued my masters in bioengineering and PhD in neuroscience. I also received postdoctoral training in Spinal Cord Injury (SCI) rehabilitation from Edgerton neuromuscular research laboratory, University of California, Los Angeles. My research is grounded in fundamentals in the field of system neuroscience with applications to prosthetics and rehabilitation following injuries in the central and/or peripheral nervous system. My major research interest is on sensory and motor control of movements with aim to understand the neural mechanisms underlying the function and recovery after injuries of the sensorimotor system. Electrophysiology, pharmacology and neurostimulation are the common techniques I apply. I also apply modern engineering techniques to utilize the neural system for prosthetic applications. Over the last few years, I have benefited from several outstanding academics and researchers around the world who have invested significant personal and professional resources into my training. As a result of these scholars mentoring, I am very inspired to strive for excellence in this highly multidisciplinary area of research.

EDUCATION AND TRAINING:

2013 – 2015: Postdoctoral Scholar, Department of Integrative Biology and Physiology, University of California Los Angeles (UCLA), California, USA.
2010 – 2013: PhD in Neuroscience, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University (PolyU), Hong Kong.
2009 – 2010: Masters in Bioengineering, Unit of Visual Rehabilitation and Neuroprosthesis (UNRV), Institute of Bioengineering, University Miguel Hernandez (UMH), Spain.

HONORS AND AWARDS:

2010: Awarded Research Postgraduate Student Scholarship at the Hong kong Polytechnic University, Hong Kong.
2009: Awarded Graduate student scholarship for masters at University Miguel Hernandez of Elche, Spain.
2003: Awarded Rajshahi University merit scholarship in recognition for good performance in undergraduation, Bangladesh.

RESEARCH PROJECTS:

Neurorehabilitation: Neuromodulation via spinal cord stimulation (SCS) and pharmacological intervention are promising therapies to restore functions after paralyzing spinal cord injuries. Even clinically complete spinal cord injuries generally have some axonal connections through the lesion area of the spinal cord. However, the caudal area from the lesion becomes silent as these few residual connections are unable to provide any significant signal transfer from the brain. Epidural spinal cord stimulation can activate these silent spinal networks. Epidural electrical stimulation of the lumbosecral spinal cord has been used in both humans and animals to improve postural and locomotor ability after a spinal cord injury. In recent studies, we are the first to demonstrate epidural cervical spinal cord stimulation to improve forelimb functions such as reaching, grasping and grip strengths in cervical injured animals.
normalized grip strength
Neuroprosthetics: Reconnection of the broken spinal cord after an injury remains elusive and controversial with stem cells therapy; while the progress of Brain-machine Interfacing (BMI) and Functional Electrical Stimulation (FES) are significant over the last few years. Contributing to this exciting field, we have developed an artificial bridge between the primary motor cortex (M1) and the limbic muscles by an embedded electronic system. This neuroprosthesis helps the neural signal to bypass the lesion of the spinal cord to restore motor functions in SCI subjects. We have also developed a miniature, multichannel wireless neurostimulator for neuroprosthetic research and applications.
a wireless neurostimulator

PUBLICATIONS:   visit google scholar